{
  "1": "#Drug1 may increase the photosensitizing activities of #Drug2.",
  "2": "#Drug1 may increase the anticholinergic activities of #Drug2.",
  "3": "The bioavailability of #Drug2 can be decreased when combined with #Drug1.",
  "4": "The metabolism of #Drug2 can be increased when combined with #Drug1.",
  "5": "#Drug1 may decrease the vasoconstricting activities of #Drug2.",
  "6": "#Drug1 may increase the anticoagulant activities of #Drug2.",
  "7": "#Drug1 may increase the ototoxic activities of #Drug2.",
  "8": "The therapeutic efficacy of #Drug2 can be increased when used in combination with #Drug1.",
  "9": "#Drug1 may increase the hypoglycemic activities of #Drug2.",
  "10": "#Drug1 may increase the antihypertensive activities of #Drug2.",
  "11": "The serum concentration of the active metabolites of #Drug2 can be reduced when #Drug2 is used in combination with #Drug1 resulting in a loss in efficacy.",
  "12": "#Drug1 may decrease the anticoagulant activities of #Drug2.",
  "13": "The absorption of #Drug2 can be decreased when combined with #Drug1.",
  "14": "#Drug1 may decrease the bronchodilatory activities of #Drug2.",
  "15": "#Drug1 may increase the cardiotoxic activities of #Drug2.",
  "16": "#Drug1 may increase the central nervous system depressant (CNS depressant) activities of #Drug2.",
  "17": "#Drug1 may decrease the neuromuscular blocking activities of #Drug2.",
  "18": "#Drug1 can cause an increase in the absorption of #Drug2 resulting in an increased serum concentration and potentially a worsening of adverse effects.",
  "19": "#Drug1 may increase the vasoconstricting activities of #Drug2.",
  "20": "#Drug1 may increase the QTc-prolonging activities of #Drug2.",
  "21": "#Drug1 may increase the neuromuscular blocking activities of #Drug2.",
  "22": "#Drug1 may increase the adverse neuromuscular activities of #Drug2.",
  "23": "#Drug1 may increase the stimulatory activities of #Drug2.",
  "24": "#Drug1 may increase the hypocalcemic activities of #Drug2.",
  "25": "#Drug1 may increase the atrioventricular blocking (AV block) activities of #Drug2.",
  "26": "#Drug1 may decrease the antiplatelet activities of #Drug2.",
  "27": "#Drug1 may increase the neuroexcitatory activities of #Drug2.",
  "28": "#Drug1 may increase the dermatologic adverse activities of #Drug2.",
  "29": "#Drug1 may decrease the diuretic activities of #Drug2.",
  "30": "#Drug1 may increase the orthostatic hypotensive activities of #Drug2.",
  "31": "The risk or severity of hypertension can be increased when #Drug2 is combined with #Drug1.",
  "32": "#Drug1 may increase the sedative activities of #Drug2.",
  "33": "The risk or severity of QTc prolongation can be increased when #Drug1 is combined with #Drug2.",
  "34": "#Drug1 may increase the immunosuppressive activities of #Drug2.",
  "35": "#Drug1 may increase the neurotoxic activities of #Drug2.",
  "36": "#Drug1 may increase the antipsychotic activities of #Drug2.",
  "37": "#Drug1 may decrease the antihypertensive activities of #Drug2.",
  "38": "#Drug1 may increase the vasodilatory activities of #Drug2.",
  "39": "#Drug1 may increase the constipating activities of #Drug2.",
  "40": "#Drug1 may increase the respiratory depressant activities of #Drug2.",
  "41": "#Drug1 may increase the hypotensive and central nervous system depressant (CNS depressant) activities of #Drug2.",
  "42": "The risk or severity of hyperkalemia can be increased when #Drug1 is combined with #Drug2.",
  "43": "The protein binding of #Drug2 can be decreased when combined with #Drug1.",
  "44": "#Drug1 may increase the central neurotoxic activities of #Drug2.",
  "45": "#Drug1 may decrease effectiveness of #Drug2 as a diagnostic agent.",
  "46": "#Drug1 may increase the bronchoconstrictory activities of #Drug2.",
  "47": "The metabolism of #Drug2 can be decreased when combined with #Drug1.",
  "48": "#Drug1 may increase the myopathic rhabdomyolysis activities of #Drug2.",
  "49": "The risk or severity of adverse effects can be increased when #Drug1 is combined with #Drug2.",
  "50": "The risk or severity of heart failure can be increased when #Drug2 is combined with #Drug1.",
  "51": "#Drug1 may increase the hypercalcemic activities of #Drug2.",
  "52": "#Drug1 may decrease the analgesic activities of #Drug2.",
  "53": "#Drug1 may increase the antiplatelet activities of #Drug2.",
  "54": "#Drug1 may increase the bradycardic activities of #Drug2.",
  "55": "#Drug1 may increase the hyponatremic activities of #Drug2.",
  "56": "The risk or severity of hypotension can be increased when #Drug1 is combined with #Drug2.",
  "57": "#Drug1 may increase the nephrotoxic activities of #Drug2.",
  "58": "#Drug1 may decrease the cardiotoxic activities of #Drug2.",
  "59": "#Drug1 may increase the ulcerogenic activities of #Drug2.",
  "60": "#Drug1 may increase the hypotensive activities of #Drug2.",
  "61": "#Drug1 may decrease the stimulatory activities of #Drug2.",
  "62": "The bioavailability of #Drug2 can be increased when combined with #Drug1.",
  "63": "#Drug1 may increase the myelosuppressive activities of #Drug2.",
  "64": "#Drug1 may increase the serotonergic activities of #Drug2.",
  "65": "#Drug1 may increase the excretion rate of #Drug2 which could result in a lower serum level and potentially a reduction in efficacy.",
  "66": "The risk or severity of bleeding can be increased when #Drug1 is combined with #Drug2.",
  "67": "#Drug1 can cause a decrease in the absorption of #Drug2 resulting in a reduced serum concentration and potentially a decrease in efficacy.",
  "68": "#Drug1 may increase the hyperkalemic activities of #Drug2.",
  "69": "#Drug1 may increase the analgesic activities of #Drug2.",
  "70": "The therapeutic efficacy of #Drug2 can be decreased when used in combination with #Drug1.",
  "71": "#Drug1 may increase the hypertensive activities of #Drug2.",
  "72": "#Drug1 may decrease the excretion rate of #Drug2 which could result in a higher serum level.",
  "73": "The serum concentration of #Drug2 can be increased when it is combined with #Drug1.",
  "74": "#Drug1 may increase the fluid retaining activities of #Drug2.",
  "75": "The serum concentration of #Drug2 can be decreased when it is combined with #Drug1.",
  "76": "#Drug1 may decrease the sedative activities of #Drug2.",
  "77": "The serum concentration of the active metabolites of #Drug2 can be increased when #Drug2 is used in combination with #Drug1.",
  "78": "#Drug1 may increase the hyperglycemic activities of #Drug2.",
  "79": "#Drug1 may increase the central nervous system depressant (CNS depressant) and hypertensive activities of #Drug2.",
  "80": "#Drug1 may increase the hepatotoxic activities of #Drug2.",
  "81": "#Drug1 may increase the thrombogenic activities of #Drug2.",
  "82": "#Drug1 may increase the arrhythmogenic activities of #Drug2.",
  "83": "#Drug1 may increase the hypokalemic activities of #Drug2.",
  "84": "#Drug1 may increase the vasopressor activities of #Drug2.",
  "85": "#Drug1 may increase the tachycardic activities of #Drug2.",
  "86": "The risk of a hypersensitivity reaction to #Drug2 is increased when it is combined with #Drug1."
}